1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Grapefruit and grapefruit juice: The presence of a grapefruit product can affect blood pressure by altering its biochemical profile.
Alcohol: While not a direct interaction, combining Cialis with a alcohol-containing diet might worsen side effects like headaches or increase heart rate in sensitive individuals.
C. Grapefruit or grapefruit juice: While Grapefruit can affect blood pressure by altering its biochemical profile, grapefruit products can increase side effects such as headaches or increase blood pressure levels. Seek medical advice before using grapefruit or grapefruit juice while consuming this interaction.
D. Combining Cialis and other medications: Cialis, like any medication, can interact with blood pressure-lowering medications, increasing side effects. Combining this with a diet that reduces alcohol intake and certain medications requires a medical consultation. Avoid combining Cialis with medications using the same active ingredient.
E.
A new report from the New York State Department of Health suggests that men who use the popular erectile dysfunction drug Viagra (Sildenafil) should stop taking their drugs because the drug is associated with a dangerous and potentially life-threatening side effect called "impotence."
The report was released Friday by a special committee that includes health care professionals, physicians, pharmacists and a variety of sexual health specialists.
The findings are based on a nationwide survey of more than 1,500 adult men, researchers said.
"The use of Viagra (Sildenafil) is associated with a higher incidence of erectile dysfunction (ED) compared to other erectile dysfunction medications," said Dr. Steven Nissen, Ph. D., director of the Department of Urology at the Mayo Clinic. "A high incidence of ED in this population could have significant implications for patients."
The National Institute on Drug Abuse and Control, or NIDA, says the drug has been linked to "major sexual problems" such as impotence and erectile dysfunction.
"In addition to these major sexual problems, Viagra may be associated with an increased risk of developing aseptic meningitis and aseptic meningitis," said Dr. Nissen. "The use of Viagra may also increase the risk of developing aseptic meningitis or aseptic meningitis with the potential for aseptic meningitis in some patients."
Viagra, also known as sildenafil, is a popular drug for treating erectile dysfunction and premature ejaculation.
"It can cause serious side effects, including priapism, which can cause permanent erectile dysfunction," NIDA said.
The drug can cause other adverse effects such as a rare heart attack and a stroke, which are serious and could be fatal.
The drug may also cause a rare condition called Raynaud's phenomenon, which occurs when the arteries become narrow or stiff, causing the heart to beat faster and more irregularly.
The drug can also cause a rare condition called "chronic venous insufficiency."
Researchers do not know whether Viagra affects men who also take nitrates.
© 2025 New York State Department of Health. All rights reserved. This material may not be published, broadcast, rewritten or redistributed in whole or in part by any means, including theUDHC or its affiliates, but permission is not required from the copyright holder. The content of this material is for informational and educational purposes only. The views and opinions expressed herein are the opinions of the attending author(s) and are not those of the Department of Health or the Department of Health nor are they considered official views and opinions expressed herein by the author(s). The views and opinions expressed in this article are solely those of the author(s).The author(s) does not receive any or all support from any such organizations, nor does the author ever have any relationship or interest in any of the products, services or materials referenced or otherwise referenced or referenced in this article.
Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Cialis use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
Read More About Cialis rx 5 mg (Cialis)Cialis can be taken with or without food. However, if you experience anything, like dizziness, or an erection that lasts more than four hours, take Cialis at least one hour before planned sexual activity.
How this medication worksDo not take Cialis if you are allergic to any of the ingredients in Cialis or its ingredients.
Cialis can also interact with nitrates, phenylpropanolamine, or sodium nitroprusside sodium, which can result in a drop in blood pressure. This may cause a condition called Priapism.
If you experience any of these, you should seek medical attention immediately.
As with all prescription medications, inform your doctor of any medical conditions you used to get yourself into while using Cialis.
Cialis can help treat erectile dysfunction (ED) in men. It is an antifungal medication that works by killing susceptible fungus cells and preventing its growth. Its primary purpose is to promote a strong erection.
Cialis does not eliminate it from your body. It only works in men with symptoms of erectile dysfunction. However, because Cialis prevents its growth from goingurden, there is a risk of it goingurden.
Cialis is a medication that contains the active ingredient tadalafil. Cialis is available in various dosages, including 10 mg and 20 mg tablets, and can be taken by individuals who are diagnosed with erectile dysfunction. Cialis is prescribed by a doctor to be taken once daily, and can be taken without regard to meals.
Cialis is a medication used to treat erectile dysfunction in men. It contains the active ingredient tadalafil, which belongs to a class of drugs called phosphodiesterase type 5 inhibitors. This medication works by relaxing the muscles in the walls of the blood vessels, allowing blood to flow into the penis during sexual stimulation. This medication is available in both brand-name and generic forms.
The usual dose of Cialis for men is 10 mg. It is prescribed for men with erectile dysfunction. The recommended starting dose for men is 10 mg, but a doctor will prescribe a lower dose of 10 mg if a man cannot tolerate other medications.
The recommended starting dose of Cialis for men is 10 mg. The dose for people who are taking the medication in tablet form is 5 mg. The recommended starting dose for those who are taking the medication in capsule form is 10 mg, but a doctor will prescribe a lower dose if a man cannot tolerate other medications.
Men taking Cialis can experience erectile dysfunction. If the person has erectile dysfunction, the doctor will prescribe a lower dosage.
Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Cialis use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
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